Conservation of mass in chemical reactions

In a chemical reaction, atoms are rearranged into new substances, but the same atoms that started the reaction are still present at the end, none are created or destroyed. Because of this, the total mass of all the reactants going into a reaction always exactly equals the total mass of all the products coming out, and chemists can use the mole as a bridge to translate these atom-for-atom mass relationships up to amounts they can actually measure in the lab, like grams.

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